Mandarin Oriental Prague

A 14th-century Dominican monastery in Malá Strana, trading medieval hush for the Mandarin Oriental's sleek contemporary calm. The cloisters remain, along with vaulted stone corridors that make every walk feel like a small pilgrimage, but the spa is the real coup: set inside the Renaissance chapel, frescoes intact on the ceiling above the treatment tables, it is among the most beautiful spas in the entire Mandarin Oriental portfolio. The pairing of 14th-century stone and 21st-century minimalism shouldn't work. At this steep, quiet end of Malá Strana, overlooking the Vltava and Prague Castle beyond, it does. 99 rooms.